This is the detail that matters most and the detail that most published material gets wrong, because it has changed repeatedly since 2022.
Erick Lindblad Preserve, 3333 Sanibel-Captiva Road. The William and Ruth Brooks Nature Trails here are partially open. Restoration from hurricane damage is still under way and about half a mile is currently walkable, one way. Foot traffic only — no bikes, no dogs. Seasonal flooding is common in parts, though drier options exist year-round. The trail begins at a trailhead in the car park to the right of the headquarters building and runs through what was historically freshwater wetland, alongside a short section of the Sanibel Slough.
Bailey Homestead Preserve, 1300 Periwinkle Way. Open, staffed and the address SCCF gives as its visiting location.
The rest of the preserve trails. Open, sunrise to sunset, daily.
The honest instruction: SCCF publishes trail-by-trail status on its own site and updates it as restoration progresses. Look at it the week you travel. Anything written before 2025 about the nature centre building as a visitor destination should be treated as out of date until you have confirmed otherwise.